The JAG1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to AGS, AHD, CD339, JAG1, and Jagged 1. This antibody recognizes Human, Mouse, and Rat antigen. The JAG1 Antibody has been validated for the following applications: Immunohistochemistry.
Description
The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis